Brain and nerve support helps bring calm and focus to the body and mind.
Discover the power of advanced neurological support with ProdromeGLIA™, a revolutionary supplement scientifically designed by Dr. Dayan Goodenowe. Built on over two decades of dedicated plasmalogen research, this omega-9 (oleic acid) plasmalogen precursor is formulated to help restore and optimize cellular function in critical areas such as brain white matter, myelin, and heart membranes.
ProdromeGLIA™ omega-9 plasmalogen precursors are the most extensively researched and only patented and validated method to restore omega-9 plasmalogens. These precursors may help prevent demyelination and neurodegeneration and reduce lipid peroxidation.
Brain and nerve support helps bring calm and focus to the body and mind.
ProdromeNEURO™ is an omega-3 (DHA) plasmalogen precursor designed to help restore and optimize cellular functions that require high levels of DHA plasmalogens, such as brain gray matter, neuron and neuromuscular synaptic function, reverse cholesterol transport, and maintaining low brain amyloid levels.
ProdromeNEURO™ DHA-plasmalogen precursors are the most extensively researched and are the only patented and validated way to restore DHA plasmalogens. These precursors may help to prevent neurodegeneration, increase reverse cholesterol transport, reduce amyloid formation, improve cognition, improve mobility, reduce lipid peroxidation, and increase anti-oxidant capacity.*
Please note: Although ProdromeNeuro™ does not contain fish, it is an omega-3 derived from algae, which naturally has a strong flavor and scent that can resemble fish. This is completely normal and expected with this type of formulation.
How To Use
Most Common: Take 2 softgels* daily or as directed by your health care professional.
Loading Dose: Take 4 to 8 softgels daily for 1 to 3 months.
*2 soft gels = 1 mL
Kindly note that our team is unable to offer detailed dosing instructions or specific protocols. Please direct these questions to a health professional.
When should I take it?: We recommend taking ProdromeGlia™ in the evening as it can have a calming effect.
WARNING
Keep out of reach of children. Do not use if the safety seal is broken or missing.
If you are pregnant, nursing, taking medication(s), or have medical conditions, contact your healthcare professional prior to using this product.
STORAGE
Store at room temperature in a cool, dry place before and after opening.
How Do Plasmalogens Work?
Plasmalogens are the matrix of the cell membranes and are the essential phospholipids that play a critical structural and functional role in the brain cell. They help maintain the proper fluidity and curvature of neuronal membranes. (Prodrome Glia™) help to ensure the correct compaction, insulation, and stability of myelin membranes, while DHA plasmalogens (Prodrome Neuro™) support neurotransmitter release, and modulate the activation of key receptors involved in neuronal survival and plasticity.³ They also reduce inflammatory signaling (e.g., by inhibiting NF-κB pathways), protecting oligodendrocytes and promoting remyelination.⁴Learn more about plasmalogens and the clinical benefits of plasmalogen optimization here.
Plasmalogens are critical to all cells.
Brain
Plasmalogens solidify and amplify the signals between neurons to optimize physical and cognitive performance.
Blood
People with high blood plasmalogens were 80% less likely to experience dementia and are proven to live longer.
Cell Walls
Plasmalogens are the building blocks of healthy cells, including building and strengthening the myelin sheath inneuronal cells.
Lungs
Plasmalogens promote and stabilize nonlamellar hexagonal phase structure and have significant antioxidant effects.
Heart
Plasmalogens strengthen the heart muscle by reinforcing the cellular structure and function and preventing premature oxidation.
Hair & Nails
Plasmalogens in nail beds and hair follicles allow richer & thicker hair and healthier & faster-growing nails.
Aging
Antioxidant free radical that acts as the body’s first line of defense against oxidation, disease and aging.
Eyes
Plasmalogens are vitally important in the membranes of neuronal tissues that link the brain and the retina. The higher the plasmalogen levels, the lower the risk of glaucoma.
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Made in the USA
Virtually all of our products are made in the USA.
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GMP Standards
All our products adhere to strict GMP quality standards.
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Clinically Proven
Scientifically designed to correct deficiencies in key molecules.
The Prodrome Brand Promise
The Prodrome Brand Promise
Every Prodrome Science product was created with a singular purpose. And that purpose is YOU. When you see the Dr. Goodenowe approved seal you can trust that this product is the result of a lifetime of acquired knowledge in biochemical mechanisms of health and disease. From the years of research and exhaustive clinical testing to the strict cGMP processes that apply to each step of our product pipeline, our team is dedicated to delivering the best biochemical essentials. Everything that you need and nothing that you don’t. Prodrome Science is a paradigm shift from today’s symptom-based healthcare system. A Prodrome-based health care system optimizes the body’s biochemistry before illness or disease has a chance to take root. Prodrome Science represents a departure from chronic disease treatment to health and vitality restoration—not just living longer, but living better.
Disclaimer
Products sold by Prodrome are intended for research, educational, and informational use only and are not intended to diagnose or treat any disease. You should always seek the advice of a physician or other healthcare provider with any questions you have regarding the diagnosis, cure, treatment, mitigation, or prevention of any disease or other medical condition or impairment of status of your health. Prodrome does not provide medical advice. None of the statements in any of our materials have been evaluated by the FDA. Any clinical applications that may be shown, are for educational purposes only. Prodrome products are not validated for clinical use. All international orders are shipped from the U.S. and are intended for Personal Use Only. Customers are responsible for complying with local laws, import regulations, and any applicable duties or restrictions.
Customer Reviews
Dr. Dayan Goodenowe
Dr. Goodenowe is a PhD neuroscientist, biochemist, synthetic organic chemist, inventor, and clinical research expert. In 1999, he invented and patented a revolutionary ion cyclotron resonance mass spectrometry technology that, for the first time in history, made it possible to comprehensively monitor human biochemistry.
Using this advanced technology, Dr. Goodenowe analyzed blood samples from tens of thousands of persons of all ages, of all races, and from multiple countries. The biochemistry of healthy persons was compared to persons suffering from disease. A diverse range of over 20 diseases from autism to dementia, and from colon cancer to heart disease was studied. The biochemistry of young versus old, and all-cause mortality was studied. This research led to his discovery that early mortality and each human disease has a biochemical prodrome.
A biochemical prodrome is a deviation from health that precedes and is predictive of a future adverse health event such as disease or death.
These discoveries led to an extensive patent portfolio of diagnostic tests for the early detection and screening of diseases such as specific cancers (colon, pancreatic, ovarian, breast, lung, prostate, and many more), autism, multiple sclerosis, Parkinson’s, ALS, Alzheimer’s, dementia, bipolar disease, schizophrenia, unipolar depression, cardiovascular disease, and others. Dr. Goodenowe created the ProdromeSCAN™ blood test which measures all of the key prodrome biomarkers and offers advanced laboratory test interpretation training for health practitioners.
Harnessing the Power of Prodrome Science
Dr. Goodenowe’s discovery of disease prodromes also revealed an opposite truth: people who maintained optimal biochemical health had an extremely low risk of disease – they had biochemical prodromes of health and longevity. The mission of Prodrome Science is to enable each and every person to attain biochemical prodromes of health using scientifically-validated, targeted biochemical nutrition.
Biochemical prodromes of disease are detectable years in advance of disease symptoms. By converting disease prodromes into health prodromes we can prevent future diseases — a victory with no battle.
The most devastating negative health prodrome discovered by Dr. Goodenowe was a deficiency in a critical group of lipids called plasmalogens. Dr. Goodenowe discovered that plasmalogen deficiencies are linked to numerous diseases such as Alzheimer’s, autism, multiple sclerosis, most cancers, and early death.
There is no viable dietary source of plasmalogens to restore plasmalogen deficiencies. Dr. Goodenowe was the first to design, invent, patent, and develop targeted plasmalogen precursors capable of restoring plasmalogens in all cells of the body. Dr. Goodenowe’s plasmalogen precursors have been extensively studied in preclinical and clinical research and are now available as dietary supplements – ProdromeNEURO™ and ProdromeGLIA™. Blood plasmalogen levels can be measured using Dr. Goodenowe’s ProdromeSCAN™ blood test.
The Prodrome Brand Promise
Every Prodrome Science product was created with a singular purpose. And that purpose is YOU. When you see the Dr. Goodenowe approved seal you can trust that this product is the result of a lifetime of acquired knowledge in biochemical mechanisms of health and disease. From the years of research and exhaustive clinical testing to the strict cGMP processes that apply to each step of our product pipeline, our team is dedicated to delivering the best biochemical essentials. Everything that you need and nothing that you don’t.The difference is in every bottle.
Customer Reviews
I take Prodrome Neuro daily and feel confident that I am protecting and nourishing my cells, which is so important as we age. I am extremely grateful that this product exists!
VERIFIED PURCHASE
The ProdromeGlia oil has a pleasant sunflower oil taste making it easy to take. The benefits I've experienced is a calming effect allowing me to focus on work during the day and relax in the evening. I've also noticed the added benefit of my skin looking better along with my hair and nails.
VERIFIED PURCHASE
This product is amazing for any inflammatory issues. Use it on myself and our dogs and have had amazing results!
VERIFIED PURCHASE
I have been taking this supplement for the past three years, almost 70, still working and feel great despite the fact that I have a gene for Alzheimer’s Disease. I strongly recommend it along with a healthy diet and lifestyle!
VERIFIED PURCHASE
I've been searching for something like this for awhile and I have found this to be one of the most effective ways to have brain clarity and support my gut as well! over all my health and wellness in high stress work environments has been aided with this!
VERIFIED PURCHASE
FAQS
What is the difference between ProdromeNeuro™ and ProdromeGlia™?
What is the difference between ProdromeNeuro™ and ProdromeGlia™?
ProdromeNeuro™ and ProdromeGlia™ are both dietary supplements that are synthetically pure, vegan plasmalogen precursors. The difference between the two lies in their fatty acid composition and targeted area of effect within the body.
ProdromeNeuro™ is an omega-3 (DHA) plasmalogen precursor that targets gray matter in the brain. DHA is extracted and purified from plant-based triglycerides and attached to a plasmalogen precursor backbone. This process makes ProdromeNeuro™ bioidentical to naturally occurring DHA plasmalogen precursors; however, there are no natural vegetarian sources that offer sufficient purity or concentration for practical use. DHA plasmalogens are found in high concentrations in the membranes of gray matter and are necessary for neuron and neuromuscular synaptic function. They are also involved in reverse cholesterol transport and maintaining low brain amyloid levels.
ProdromeGlia™ is an omega-9 (oleic acid) plasmalogen precursor that targets white matter in the brain. Like ProdromeNeuro™, it is bioidentical to naturally occurring oleic acid plasmalogen precursors but cannot be practically derived from natural vegetarian sources. The oleic acid used to make ProdromeGlia™ is extracted and purified from plant-based triglycerides. White matter is largely made up of myelin, which requires high levels of omega-9 plasmalogens to function.
Both plasmalogen precursors are manufactured in a cGMP facility in Temecula, CA, USA
How do I decide between ProdromeNeuro or ProdromeGlia?
How do I decide between ProdromeNeuro or ProdromeGlia?
To help you choose between ProdromeNeuro™ and ProdromeGlia™, consider the following:
Your age: Plasmalogen levels naturally decline after the age of 50. ProdromeNeuro™ and ProdromeGlia™ can help support cellular health, protect against oxidative stress, and ensure proper cell membrane function.
Your cognitive health: People with dementia experience a rapid decline in plasmalogens, particularly omega-3 plasmalogens. If you are concerned about cognitive decline, you may want to consider ProdromeNeuro™.
Your overall health: White matter degeneration can affect many neurological functions, including movement, sensation, and thinking. If you are concerned about the health of your myelin and white matter, you may want to consider ProdromeGlia™.
Evaluating Your Needs
It is important to note that plasmalogen deficiencies may vary from person to person. We recommend taking the ProdromeScan™ blood test, developed by Dr. Goodenowe, to measure your plasmalogen levels. This test can help you to determine which type of plasmalogen precursor would be most beneficial for you.
While we recommend taking the blood test, it is not required when trying Prodrome plasmalogen products. Many people take ProdromeNeuro™ in the morning because it has a slightly stimulating effect and ProdromeGlia™ in the evening because it has a calming effect.
It is essential to consult with a healthcare professional to determine the best course of action for your individual needs. They can help you evaluate your health history and make recommendations based on your specific circumstances.
How are your Prodrome Plasmalogen products different from others?
How are your Prodrome Plasmalogen products different from others?
Other plasmalogen products available are typically derived from animal sources and contain very low concentrations of plasmalogens. For example, one product provides just 0.5mg of plasmalogen per capsule (30mg per bottle), while another contains 4mg per capsule (240mg per bottle). In contrast, Prodrome Plasmalogen products offers a significantly higher concentration, with 900mg of plasmalogens per serving and 27,000mg per bottle—delivering more in a single serving than other products offer in an entire bottle.
Additionally, our ProdromeNeuro™ and ProdromeGlia™ products are plasmalogen precursors, specifically formulated by Dr. Goodenowe for optimal absorption and bioavailability. These precursors are designed to bypass gut degradation, allowing them to quickly and effectively restore plasmalogen levels in the body.
What time of day should I take Plasmalogens? Can I take with food or other supplements?
What time of day should I take Plasmalogens? Can I take with food or other supplements?
You can take ProdromeNeuro and ProdromeGlia at any time of day. They can be taken with or without food. They can be taken with any other supplements.
However, many prefer taking ProdromeNeuro in the morning and ProdromeGlia in the evening.
How much Plasmalogen Supplement should I take? Do I have to keep taking it every day?
How much Plasmalogen Supplement should I take? Do I have to keep taking it every day?
The recommended dose is 900mg each day. Some individuals prefer taking a loading dose of 2-4x the daily dose for 1 to 3 months. It is recommended to continue taking the plasmalogen supplement every day. Always consult your healthcare provider to determine what is best for you.
Can I mix the Plasmalogen Oil with food?
Can I mix the Plasmalogen Oil with food?
Yes, if you prefer to mix with food you can.
Can I mix the Plasmalogen Oil with a hot beverage?
Can I mix the Plasmalogen Oil with a hot beverage?
Yes, you can mix with a hot beverage.
Are your products tested for purity and contaminants?
Are your products tested for purity and contaminants?
Yes, we test our products using a third-party lab.
Where should I store the products? What is the shelf life?
Where should I store the products? What is the shelf life?
The ProdromeNeuro soft gels and ProdromeGlia softgels, as well as ProdromeGlia plasmalogen liquid oil can be stored at room temperature, in a cool, dry place both before and after opening.
Store ProdromeNeuro plasmalogen liquid oil in the refrigerator when you receive it and after opening to maintain freshness. ProdromeNeuro can be kept at room temperature, but we recommend to store in the fridge for freshness. All other supplements can be stored in a cool, dry place.
ProdromeNeuro plasmalogen oil has a shelf life of 18 months prior to opening (once opened it is best to use within 30 days). ProdromeGlia plasmalogen oil has a shelf life of 24 months (once opened it is best to use within 90 days). The ProdromeNeuro and ProdromeGlia softgels have a shelf life of 24 months.
All of the oils have a manufacturing date printed on the bottle and this should not be confused with an expiration date.
Always check the product packaging for the most up to date information.
Are your supplements vegan, non-gmo, organic?
Are your supplements vegan, non-gmo, organic?
Always refer to the product listings for the most up to date information. Our plasmalogen oil supplements are vegan, however the softgels are not vegan as the soft gel capsule is made with gelatin. They are not certified non-GMO but the ingredients are all non-GMO. They are not certified organic.
Why does ProdromeNeuro have a strong taste and smell?
Why does ProdromeNeuro have a strong taste and smell?
ProdromeNeuro Oil may have a "fishy" smell or taste due to the Omega-3, which is sourced from purified algae.
Does ProdromeNeuro have to be refrigerated at all times?
Does ProdromeNeuro have to be refrigerated at all times?
ProdromeNeuro softgels should be stored at room temperature in a cool, dry place. It is fine to store them in the fridge or freezer for long term storage, but it is not necessary.
ProdromeNeuro plasmalogen liquid oil should be stored in the refrigerator when received and after opening to preserve freshness. The cold chain does not have to be maintained strictly and can be transported at room temperature.